{"_buckets": {"deposit": "abc5f0aa-828e-4d67-b781-20e793169268"}, "_deposit": {"created_by": 15, "id": "222", "owners": [15], "pid": {"revision_id": 0, "type": "depid", "value": "222"}, "status": "published"}, "_oai": {"id": "oai:tohoku-mpu.repo.nii.ac.jp:00000222", "sets": ["6"]}, "author_link": [], "item_1_biblio_info_14": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2005-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "52", "bibliographicPageEnd": "110", "bibliographicPageStart": "105", "bibliographic_titles": [{"bibliographic_title": "東北薬科大学研究誌", "bibliographic_titleLang": "ja"}, {"bibliographic_title": "Journal of Tohoku Pharmaceutical University", "bibliographic_titleLang": "en"}]}]}, "item_1_creator_6": {"attribute_name": "著者名(日)", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "溝口, 広一", "creatorNameLang": "ja"}, {"creatorName": "ミゾグチ, ヒロカズ", "creatorNameLang": "ja-Kana"}, {"creatorName": "Mizoguchi, Hirokazu", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "成田, 年", "creatorNameLang": "ja"}, {"creatorName": "ナリタ, ミノル", "creatorNameLang": "ja-Kana"}, {"creatorName": "Narita, Minoru", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "澤井, 敏樹", "creatorNameLang": "ja"}, {"creatorName": "サワイ, トシキ", "creatorNameLang": "ja-Kana"}, {"creatorName": "Sawai, Toshiki", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "渡辺, 千寿子", "creatorNameLang": "ja"}, {"creatorName": "ワタナベ, チズコ", "creatorNameLang": "ja-Kana"}, {"creatorName": "Watanabe, Chizuko", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "長瀬, 博", "creatorNameLang": "ja"}, {"creatorName": "ナガセ, ヒロシ", "creatorNameLang": "ja-Kana"}, {"creatorName": "Nagase, Hiroshi", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "櫻田, 忍", "creatorNameLang": "ja"}, {"creatorName": "サクラダ, シノブ", "creatorNameLang": "ja-Kana"}, {"creatorName": "Sakurada, Shinobu", "creatorNameLang": "en"}]}]}, "item_1_description_11": {"attribute_name": "抄録(日)", "attribute_value_mlt": [{"subitem_description": "The involvement of endogenous opioid peptides and opioid receptors in supraspinal site on the antinociception induced by cold water swimming was determined using the mouse tail-flick test. The mice forced to swim in cold water for 3 min, showed the marked antinociception. The antinociception induced by cold water swimming was significantly attenuated by intracerebroventricularly (i.c.v.) pretreatment with antiserum against β-endorphin, but not against dynorphin A or [Leu^5] enkephalin. On the other hand, the antinociception was not affected by i.c.v. pretreatment with μ-opioid receptor antagonists β-funaltrexamine and D-Phe-cyclo-(Cys-Tyr-D-Trp-Orn-Thr-Pen)-Thr-NH_2, δ-opioid receptor antagonists naltrindole, 7-benzylidene naltrexone and naltriben, or κ-opioid receptor antagonist nor-binaltorphimine. The present results suggest that the antinociception induced by cold water swimming may be mainly mediated through the release of β-endorphin in the supraspinal site, which act on β-endorphin-sensitive non-μ-, non-δ-, and non-κ-opioid receptor, so called putative ε-opioid receptor.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_1_source_id_13": {"attribute_name": "雑誌書誌ID", "attribute_value_mlt": [{"subitem_source_identifier": "AA1149311X", "subitem_source_identifier_type": "NCID"}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2005-12-01"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00004373134.pdf", "filesize": [{"value": "525.8 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_11", "mimetype": "application/pdf", "size": 525800.0, "url": {"label": "KJ00004373134", "objectType": "fulltext", "url": "https://tohoku-mpu.repo.nii.ac.jp/record/222/files/KJ00004373134.pdf"}, "version_id": "d29b15ca-b7b6-4b60-8960-a6356d6c2a2b"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Antinociception", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "cold water swimming", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "environmental stress", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "supraspinal", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "β-endorphin", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "ε-opioid receptor", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "冷水強制水泳誘発抗侵害作用の発現における脳内β-endorphinならびにεオピオイド受容体の関与", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "冷水強制水泳誘発抗侵害作用の発現における脳内β-endorphinならびにεオピオイド受容体の関与", "subitem_title_language": "ja"}, {"subitem_title": "Involvement of endogenous β-endorphin and ε-opioid receptors in supraspinal site on the cold water swimming-induced antinociception in mice", "subitem_title_language": "en"}]}, "item_type_id": "1", "owner": "15", "path": ["6"], "permalink_uri": "https://tohoku-mpu.repo.nii.ac.jp/records/222", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2005-12-01"}, "publish_date": "2005-12-01", "publish_status": "0", "recid": "222", "relation": {}, "relation_version_is_last": true, "title": ["冷水強制水泳誘発抗侵害作用の発現における脳内β-endorphinならびにεオピオイド受容体の関与"], "weko_shared_id": -1}
冷水強制水泳誘発抗侵害作用の発現における脳内β-endorphinならびにεオピオイド受容体の関与
https://tohoku-mpu.repo.nii.ac.jp/records/222
https://tohoku-mpu.repo.nii.ac.jp/records/222