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Preparation and characterization of low-crystallized hydroxyapatite nanoporous plates and granules
https://osaka-dent.repo.nii.ac.jp/records/45
https://osaka-dent.repo.nii.ac.jp/records/458394e9d0-f78c-4380-af9d-a99b7067365d
名前 / ファイル | ライセンス | アクション |
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学位論文 (1.2 MB)
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論文内容要旨・審査結果要旨 (130.2 kB)
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2016-08-01 | |||||
本文言語 | ||||||
言語 | eng | |||||
タイトル | ||||||
タイトル | Preparation and characterization of low-crystallized hydroxyapatite nanoporous plates and granules | |||||
著者 |
上平, 真代
× 上平, 真代× Uehira, Mayo |
|||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Hydroxyapatite | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Nanoparticle | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Assembly | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Transparency | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Nanopore | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Protein adsorption | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||
資源タイプ | doctoral thesis | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We examined the conditions for preparing nanoporous hydroxyapatite (HAp) plates and granules by assembling low-crystallinity HAp nanoparticles without template/binder molecules or high-temperature/pressure treatments. We first prepared HAp nanoparticles with different particle sizes and then the nanoporous plate or granule was prepared by drying an aqueous dispersion of HAp nanoparticles on an oil substrate. The hydrophobic oil substrate was preferable to prevent crack formation in HAp plates. The size of the HAp plate could be controlled by the concentration of HAp dispersion, and millimeter-sized granules were obtained by drying a small volume of HAp dispersion on/in the oil substrate. The nanoparticle-assembled HAp had nanosized pores, and the pore size could be changed by adjusting the size of the HAp nanoparticles used. It was found that both hydrophilic and hydrophobic liquids could infiltrate inside the nanopores. The nanoporous HAp granules also could adsorb and release proteins, and the protein adsorption and release delayed in the presence of the nanopores. | |||||
学位名 | ||||||
学位名 | 博士(歯学) | |||||
学位授与機関 | ||||||
学位授与機関識別子Scheme | kakenhi | |||||
学位授与機関識別子 | 34408 | |||||
学位授与機関名 | 大阪歯科大学 | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2014-03-07 | |||||
学位授与番号 | ||||||
学位授与番号 | 甲第721号 |