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In vivo bioactivity of porous polyetheretherketone with a foamed surface
https://osaka-dent.repo.nii.ac.jp/records/161
https://osaka-dent.repo.nii.ac.jp/records/1619123d5aa-08aa-4029-a00c-96fdc1b03a39
名前 / ファイル | ライセンス | アクション |
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学位論文 (5.8 MB)
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論文内容要旨・審査結果要旨 (216.4 kB)
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2017-04-19 | |||||
本文言語 | ||||||
言語 | eng | |||||
タイトル | ||||||
タイトル | In vivo bioactivity of porous polyetheretherketone with a foamed surface | |||||
著者 |
稗田, 彩人
× 稗田, 彩人× Hieda, Ayato |
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キーワード | ||||||
主題Scheme | Other | |||||
主題 | bioactivity|polyetheretherketone| foamed surface |porous | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||
資源タイプ | doctoral thesis | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The in vivo bioactivity of porous polyetheretherketone (PEEK) with a foamed surface was evaluated using rabbit femoral bone. Cylindrical porous PEEK scaffolds, with pore diameter of 550 μm and porosity of 70%, were first prepared and immersed in 98% sulfuric acid, and then washed and immersed in 3 M potassium carbonate solution used as a foaming reagent. Numerous open pores of various sizes, as well as new functional groups, were visualized on the treated PEEK surface by scanning electron microscopy and X-ray photoelectron spectroscopy, respectively. Micro computed tomography (micro-CT) showed that the volumetric density of treated PEEK was higher than that of bare PEEK at 8 weeks after surgery (P<0.05). Additionally, von Kossa staining indicated ingrowth of mature new bone tissue at 4 weeks relative to the bare PEEK group. Our data indicate that surface-treated PEEK exhibited improved bioactivity in vivo. | |||||
学位名 | ||||||
学位名 | 博士(歯学) | |||||
学位授与機関 | ||||||
学位授与機関識別子Scheme | kakenhi | |||||
学位授与機関識別子 | 34408 | |||||
学位授与機関名 | 大阪歯科大学 | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2017-03-10 | |||||
学位授与番号 | ||||||
学位授与番号 | 甲第803号 |