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The Effect of Different Surgical Instruments for Bone Regeneration under the Surgery of Bone Defect on Rat Calvaria
https://osaka-dent.repo.nii.ac.jp/records/338
https://osaka-dent.repo.nii.ac.jp/records/33813966bc5-4981-4257-926e-bac11105ff1b
| 名前 / ファイル | ライセンス | アクション |
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学位論文 (1.0 MB)
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論文内容要旨・審査結果要旨 (202.9 kB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||||||||
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| 公開日 | 2022-06-27 | |||||||||||
| 本文言語 | ||||||||||||
| 言語 | eng | |||||||||||
| タイトル | ||||||||||||
| タイトル | The Effect of Different Surgical Instruments for Bone Regeneration under the Surgery of Bone Defect on Rat Calvaria | |||||||||||
| 著者 |
古森, 喬
× 古森, 喬
× Furumori, Takashi
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| キーワード | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Bone regeneration | |||||||||||
| キーワード | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Surgical instruments | |||||||||||
| キーワード | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Calvaria | |||||||||||
| キーワード | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Ultrasonic knife | |||||||||||
| キーワード | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Trephine bur | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||||||||
| 資源タイプ | doctoral thesis | |||||||||||
| アクセス権 | ||||||||||||
| アクセス権 | open access | |||||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||||
| 抄録 | ||||||||||||
| 内容記述タイプ | Abstract | |||||||||||
| 内容記述 | In this study, we compared the healing process of bone defects treated with a trephine bur with those treated with an ultrasonic knife using a critical-sized bone defect model on rat calvaria. Nine-millimeter critical-size bone defects were prepared using both instruments in the calvaria of adult Sprague-Dawley rats. One and four weeks after the osteotomy, we performed a histomorphometric analysis to evaluate bone regeneration around the cutting surface. Quantitative micro-computed tomography analyses of the bone volume in both groups suggested that ultrasonic knife surgery resulted in superior bone formation compared to that in trephine bur surgery. Furthermore, at the cutting surface, the ultrasonic knife treatment retained the alkaline phosphatase activity and new bone formation, which was identified using calcein staining, even one week after surgery. Considering the speed and volume of bone regeneration, the ultrasonic knife is likely to be the preferred over the trephine bur to perform osteotomies in implant surgery. |
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| 学位名 | ||||||||||||
| 学位名 | 博士（歯学） | |||||||||||
| 学位授与機関 | ||||||||||||
| 学位授与機関識別子Scheme | kakenhi | |||||||||||
| 学位授与機関識別子 | 34408 | |||||||||||
| 学位授与機関名 | 大阪歯科大学 | |||||||||||
| 学位授与年月日 | ||||||||||||
| 学位授与年月日 | 2022-06-22 | |||||||||||
| 学位授与番号 | ||||||||||||
| 学位授与番号 | 乙第1641号 | |||||||||||
