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Calcium Flux During Growth in Sham-operated and Ovariectomized Rats
https://showa.repo.nii.ac.jp/records/1074
https://showa.repo.nii.ac.jp/records/1074d52ae810-ff73-4ebc-9652-71482f6a7ae6
名前 / ファイル | ライセンス | アクション |
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D31_1.pdf (1.1 MB)
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Item type | 学内発行雑誌 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2016-12-21 | |||||
タイトル | ||||||
タイトル | Calcium Flux During Growth in Sham-operated and Ovariectomized Rats | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ | departmental bulletin paper | |||||
著者 |
MOROHASHI, Tomio
× MOROHASHI, Tomio× KARAKAWA, Akiko× SAKAI, Nobuhiro× YAMADA, Shoji |
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書誌情報 |
Dental medicine research 巻 31, 号 1, p. 1-6, 発行日 2011-03 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The details of calcium flux during growth were examined in female rats. Forty-two 53-day-old rats were divided into 2 groups and underwent either bilateral laparotomy (n=21) or bilateral ovariectomy (n=21) at age 60 days. Rats were equally divided into 6 sub-groups during the experimental period. Rats were given a purified diet (0.5% Ca and 0.35% Pi) throughout the experiment. Calcium balance and 45Ca kinetics studies using an open twocompartment model were performed over a 3-day period when rats were 74, 88 and 116 days old. A simple calcium balance study, using the last group, was carried out at age 102 days. The results showed that age affected calcium intake, apparent intestinal calcium absorption, urinary calcium output, calcium excretion into the intestine and the calcium balance in both groups. The peak values of calcium from bone (Vo−) and calcium into bone (Vo+) were found at 88 days in sham-operated (SH) rats. Differences between the two groups with respect to Vo− and Vo+ were observed at 74 days; the values at 74 days in ovariectomized rats were higher than those in SH rats. Taken together, our results suggest that ovariectomy might induce high bone-turnover, which occurs earlier and is greater than that in SH rats, and thereafter the value is similar to that in SH rats. | |||||
DOI | ||||||
関連識別子 | 10.7881/dentalmedres.31.1 | |||||
出版者 | ||||||
出版者 | 昭和大学・昭和歯学会 | |||||
ISSN | ||||||
収録物識別子 | 1882-0719 | |||||
著者版フラグ | ||||||
出版タイプ | VoR |